Effects of human amniotic fluid on cartilage regeneration from free perichondrial grafts in rabbits


Ozgenel G., Filiz G., Ozcan M.

BRITISH JOURNAL OF PLASTIC SURGERY, vol.57, no.5, pp.423-428, 2004 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 5
  • Publication Date: 2004
  • Doi Number: 10.1016/j.bjps.2003.12.021
  • Title of Journal : BRITISH JOURNAL OF PLASTIC SURGERY
  • Page Numbers: pp.423-428

Abstract

After the chondrogenic potential of free grafts of perichondrium was shown in several experimental studies, perichondrium has been used to reconstruct cartilage tissue in various clinical situations. This study investigates the effects of human amniotic fluid on neochondrogenesis from free perichondrial grafts in a rabbit model. Since this fluid contains high concentrations of hyaluronic acid, hyaluronic acid-stimulating activator, growth factors, and extracellular matrix precursors during the second trimester, it may have a stimutating effect on neochondrogenesis.