Effects of human amniotic fluid on cartilage regeneration from free perichondrial grafts in rabbits

Ozgenel G., Filiz G., Ozcan M.

BRITISH JOURNAL OF PLASTIC SURGERY, vol.57, no.5, pp.423-428, 2004 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 5
  • Publication Date: 2004
  • Doi Number: 10.1016/j.bjps.2003.12.021
  • Journal Name: BRITISH JOURNAL OF PLASTIC SURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.423-428
  • Bursa Uludag University Affiliated: No

Abstract

After the chondrogenic potential of free grafts of perichondrium was shown in several experimental studies, perichondrium has been used to reconstruct cartilage tissue in various clinical situations. This study investigates the effects of human amniotic fluid on neochondrogenesis from free perichondrial grafts in a rabbit model. Since this fluid contains high concentrations of hyaluronic acid, hyaluronic acid-stimulating activator, growth factors, and extracellular matrix precursors during the second trimester, it may have a stimutating effect on neochondrogenesis.