Native Valve Endocarditis Caused by<i> Stenotrophomonas</i><i> maltophilia:</i> A Rare Case

ÖZDEMİR E., HEPER Y., ÖNAL U., ŞENOCAK H., Gullulu S., ÖZAKIN C.

KLIMIK JOURNAL, cilt.39, sa.1, ss.64-68, 2026 (ESCI, Scopus, TRDizin) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 1
  • Basım Tarihi: 2026
  • Doi Numarası: 10.36519/kd.2026.5302
  • Dergi Adı: KLIMIK JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, CINAHL, EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.64-68
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Stenotrophomonas maltophilia is an uncommon cause of infective endocarditis (IE). This opportunistic pathogen poses significant therapeutic challenges due to its ability to form biofilms and its intrinsic resistance to multiple antibiotics. While trimethoprim-sulfamethoxazole (TMP-SMX) and quinolones are considered first-line therapies, prolonged targeted treatment may result in serious adverse effects. Established risk factors for S. maltophilia infection include a history of prosthetic valve surgery, presence of a central venous catheter, and prior use of broad-spectrum antibiotics. This report describes a case of successfully treated native valve endocarditis in a patient receiving hemodialysis through permanent catheter. The case is discussed in the context of the current literature to illustrate clinical experience and highlight therapeutic challenges.