Current treatment options for patients with initially unresectable isolated colorectal liver metastases

Kanat O.

WORLD JOURNAL OF CLINICAL ONCOLOGY, vol.7, no.1, pp.9-14, 2016 (ESCI) identifier identifier identifier

  • Publication Type: Article / Editorial Material
  • Volume: 7 Issue: 1
  • Publication Date: 2016
  • Doi Number: 10.5306/wjco.v7.i1.9
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.9-14
  • Bursa Uludag University Affiliated: Yes


The development of liver metastases is a common clinical entity in the clinical course of colorectal cancer. For patients with isolated liver involvement, surgical resection is the only treatment that can provide a chance of prolonged survival and cure. However, most of these patients are not initially eligible for the surgery. Selected patients with initially considered to have unresectable disease may become resectable after systemic (chemotherapy +/- biological therapy) and loco-regional treatment modalities including hepatic arterial infusion. Patients who have colorectal liver metastases ideally should be referred to a multidisciplinary cancer care team in order to identify the most optimal management approach.