Neuroprotective Effects of Postconditioning on Lipid Peroxidation and Apoptosis after Focal Cerebral Ischemia/Reperfusion Injury in Rats

Abas F., ALKAN T., GÖREN B., Taskapilioglu O., SARANDÖL E., Tolunay S.

TURKISH NEUROSURGERY, vol.20, no.1, pp.1-8, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 1
  • Publication Date: 2010
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1-8
  • Keywords: Antioxidant enzymes, Ischemia reperfusion injury, Lipid peroxidation, Neuroprotection, Postconditioning, REDUCES INFARCT SIZE, ARTERY OCCLUSION, CYTOCHROME-C, BRAIN-INJURY, REPERFUSION, ISCHEMIA, PROTECTS, STROKE, MITOCHONDRIA, TRANSITION
  • Bursa Uludag University Affiliated: Yes


AIM: Apoptosis after cerebral ischemia/reperfusion (I/R) injury leads to the process of cell death. The deal therapeutic approach would target the apoptosis after I/R. Ischemic postconditioning is a recently discovered neuroprotective strategy that involves the application of brief mechanical reperfusion with a specific algorithm at the onset of reperfusion following an ischemic period.