Lack of genotoxicity in medical oncology nurses handling antineoplastic drugs: Effect of work environment and protective equipment

Gulten T., Evke E., ERCAN İ., EVRENSEL T., Kurt E., Manavoglu O.

WORK-A JOURNAL OF PREVENTION ASSESSMENT & REHABILITATION, vol.39, no.4, pp.485-489, 2011 (SSCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 39 Issue: 4
  • Publication Date: 2011
  • Doi Number: 10.3233/wor-2011-1198
  • Journal Name: WORK-A JOURNAL OF PREVENTION ASSESSMENT & REHABILITATION
  • Journal Indexes: Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.485-489
  • Keywords: Occupational exposure, health care workers, sister chromatid exchange assay, closed system device, biological monitoring, SISTER-CHROMATID EXCHANGES, OCCUPATIONAL-EXPOSURE, ANTICANCER DRUGS, BUCCAL CELLS, DNA-DAMAGE, LYMPHOCYTES, RISK, CONTAMINATION, CHROMOSOME, INDUCTION
  • Bursa Uludag University Affiliated: Yes

Abstract

Objective: In this study we aimed to investigate the genotoxic effects of antineoplastic agents in occupationaly exposed oncology nurses. Genotoxic effects mean the disruptive effects in the integrity of DNA and they are associated with cancer development. Biomonitoring of health care workers handling antineoplastic agents is helpful for the evaluation of exposure to cytostatics.