Insulin-Like Growth Factor-1 and Morbidities of Prematurity: Bronchopulmonary Dysplasia, Retinopathy of Prematurity, Intraventricular Hemorrhage and Necrotizing Enterocolitis


DoRUM B. A. , Koksal N. , ÖZKAN H. , Cakir S. C. , Yilmaz C., ÖZGÜR T. , ...More

GUNCEL PEDIATRI-JOURNAL OF CURRENT PEDIATRICS, vol.17, no.2, pp.189-199, 2019 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.32941/pediatri.600317
  • Title of Journal : GUNCEL PEDIATRI-JOURNAL OF CURRENT PEDIATRICS
  • Page Numbers: pp.189-199

Abstract

INTRODUCTION: Insulin-like growth factor-1 (IGF-1) is important for fetal and postnatal development. After premature births, serum IGF-1 concentrations rapidly decrease and can stay at much lower levels than during the intrauterine period. In this study, we aimed to ascertain whether IGF-1 is associated with morbidities of prematurity such as bronchopulmonary dysplasia (BPD), retinopathy of prematurity (ROP), intraventricular hemorrhage (IVH), and necrotizing enterocolitis (NEC), and is a useful predictor of these diseases.