Effectiveness of GFAP in Determining Neuronal Damage in Rats with Induced Head Trauma

Cikriklar H. İ., Uysal O., Ekici M. A., Ozbek Z., Turgut Cosan D., Yucel M., ...More

TURKISH NEUROSURGERY, vol.26, no.6, pp.878-889, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 6
  • Publication Date: 2016
  • Doi Number: 10.5137/1019-5149.jtn.13946-15.2
  • Journal Name: TURKISH NEUROSURGERY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.878-889
  • Keywords: Traumatic brain injury, Experimental, GFAP, Astrocyte, Rat, FIBRILLARY ACIDIC PROTEIN, COMA SCALE SCORE, BRAIN-INJURY, COMPUTED-TOMOGRAPHY, INTRACRANIAL INJURY, CHILDREN, MODEL, CT, EXPRESSION, ASTROGLIOSIS
  • Bursa Uludag University Affiliated: Yes

Abstract

AIM: To determine whether the serum level of glial fibrillary acidic protein (GFAP), an important indicator of neuron damage, correlates with the extent of tissue damage in the rat with induced head trauma and to obtain data in order to avoid unnecessary cranial computed tomography analyses.