EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, vol.18, no.1, pp.10-27, 2014 (SCI-Expanded)
Article / Article
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Traumatic brain injury, Etanercept, Lithium chloride, TNF-alpha, NECROSIS-FACTOR-ALPHA, SPINAL-CORD-INJURY, FIBRILLARY ACIDIC PROTEIN, FOCAL CEREBRAL-ISCHEMIA, TAU-PROTEIN, RHEUMATOID-ARTHRITIS, NEURONAL DAMAGE, TNF-ALPHA, EXPRESSION, MODEL
Bursa Uludag University Affiliated:
OBJECTIVE: Studies in animals have provided key evidence that antagonizing TNF-alpha is a viable therapeutic strategy for diffuse severe brain injury. This study is planned to prevent post-traumatic secondary tissue damages in rat diffuse severe brain injury model, which is induced by alone or combined administration of Etanercept and lithium chloride (LiCl).