Determination of the effect of a monensin capsule (continuous-release capsules) on metabolic parameters in transition dairy cows


KASAP S., Erturk M., MECİTOĞLU Z., Dulger H., Babaeski S., KENNERMAN E.

MEDYCYNA WETERYNARYJNA-VETERINARY MEDICINE-SCIENCE AND PRACTICE, vol.76, no.9, pp.512-516, 2020 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 76 Issue: 9
  • Publication Date: 2020
  • Doi Number: 10.21521/mw.6435
  • Journal Name: MEDYCYNA WETERYNARYJNA-VETERINARY MEDICINE-SCIENCE AND PRACTICE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, CAB Abstracts, Veterinary Science Database
  • Page Numbers: pp.512-516
  • Keywords: monensin, transition period, metabolites, milk yield, NEGATIVE-ENERGY BALANCE, DRY-MATTER INTAKE, REPRODUCTIVE-PERFORMANCE, MILK-PRODUCTION, SUBCLINICAL KETOSIS, SODIUM MONENSIN, FATTY LIVER, PREPARTUM, CATTLE, SUPPLEMENTATION
  • Bursa Uludag University Affiliated: Yes

Abstract

Monensin is an ionophore antibiotic that changes the population of rumen bacteria. The aim of this study was to determine the effects of a monensin controlled-release capsule administered 3 weeks before calving on blood metabolites (serum beta-hydroxybutiric acid (BHBA), cholesterol (CHOL), urea, creatinine (CREA), gamma glutamyl transferase (GGT), aspartate aminotransferase (AST), total protein (TP), phosphorus (P), magnesium (Mg+), calcium (Ca++), glucose (GLU) and plasma non-esterified fatty acids (NEFA) concentration) and milk yield before and after calving. A total of 50 Holstein-Friesian cows were selected from the same flock. Blood samples were taken 3 weeks before the expected calving date and during weeks 1, 2, 4, 6, and 8 after calving. The cows were divided into two groups: a study group (Group M, n = 40) and a control group (Group C, n = 10). Group M received orally a cylindrical device (Kexxtone, ELANCO Animal Health, Guelph, ON, Canada), and group C received no treatment. BHBA and NEFA were lower (P < 0.05) in group M compared with group C in weeks 6 and 8 after calving. GLU was higher (P < 0.05) in group M compared with group C in week 4 after calving. Urea was higher (P < 0.05) in group M compared with group C in week 1 after calving. There was no statistically significant difference (P <0.05) between the two groups in milk yields. Although milk yield was similar in both groups, the changes in the concentrations of BHBA, NEFA, GLU and urea show that a monensin CRC could be used as a glycogenic precursor.