Protective effects of long term dietary restriction on swimming exercise-induced oxidative stress in the liver, heart and kidney of rat


Aydin C. , Ince E., Koparan Ş. , Cangul İ. T. , Naziroglu M., Ak F.

CELL BIOCHEMISTRY AND FUNCTION, vol.25, no.2, pp.129-137, 2007 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 25 Issue: 2
  • Publication Date: 2007
  • Doi Number: 10.1002/cbf.1279
  • Title of Journal : CELL BIOCHEMISTRY AND FUNCTION
  • Page Numbers: pp.129-137
  • Keywords: dietary restriction, exercise, oxidative stress, antioxidant enzyme, CALORIC RESTRICTION, FOOD RESTRICTION, ANTIOXIDANT ENZYMES, SKELETAL-MUSCLE, LIFE-SPAN, GLUTATHIONE, MICE, AGE, EXPRESSION, GENERATION

Abstract

In this study, we evaluated the hypothesis that long term dietary restriction would have beneficial effects on the oxidative stress and antioxidant enzyme systems in liver, heart and kidney in adult mate rats undergoing different intensities of swimming exercise. Sixty male, Sprague-Dawley rats were assigned as either dietary restricted on every other week day (DR) or fed ad libitum (AL) groups, and each group was further subdivided into sedentary, endurance swimming exercise training (submaximal exercise) and exhaustive swimming exercise (maximal exercise) groups. Animals in the submaximal exercise group swam 5 days/week for 8 weeks, while maximal exercise was performed as an acute bout of exercise.