Genetic variation at the OLR1, ANXA9, MYF5, LTF, IGF1, LGB, CSN3, PIT1, MBL1, CACNA2D1, and ABCG2 loci in Turkish Grey Steppe, Anatolian Black, and East Anatolian Red cattle


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Çobanoğlu Ö., Ardıçlı S.

TURKISH JOURNAL OF VETERINARY AND ANIMAL SCIENCES, vol.46, pp.494-504, 2022 (Peer-Reviewed Journal)

  • Publication Type: Article / Article
  • Volume: 46
  • Publication Date: 2022
  • Journal Name: TURKISH JOURNAL OF VETERINARY AND ANIMAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded, Scopus, Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.494-504

Abstract

Native breeds are excellent sources of genetic variation. Anatolian native breeds are relatives of the first cattle domesticated

and are ancestors of many European breeds. Therefore, this study aimed to evaluate the genetic variation of OLR1, ANXA9, MYF5,

LTF, IGF1, LGB, CSN3, PIT1, MBL1, CACNA2D1, and ABCG2 markers in Turkish Grey Steppe, Anatolian Black, and East Anatolian

Red cattle. The analysis included 367 cattle and the genotyping was performed by the PCR-RFLP. Population genetics indices including

heterozygosity, the number of effective alleles, the polymorphism information content, fixation index, and the level of possible variability

realization, and moreover, the genetic diversity parameters including Shannon–Weaver diversity index and Simpson dominance index

were estimated. Hardy–Weinberg equilibrium was evaluated based on the number of individuals per genotype. Native breeds exhibited

admissible population genetics and diversity levels. There was no animal with the MYF5-AA, IGF1-CC, LGB-BB, CSN3-BB, CACNA2D1-

GG, and ABCG2-AC genotypes in the Anatolian Black breed. The frequencies of the genotypes/alleles favorable for milk production

traits were remarkably low in all breeds. These findings could provide useful information on the genetic variation of Anatolian native

cattle and the genetic investigations of resistance and health traits in bovine breeding and genetics.