Recommendations for the Treatment of Invasive Fungal Infections in Hematological Malignancies: A Critical Review of Evidence and Turkish Expert Opinion (TEO-1)

AKAN H., Aydin S. O., SALTOĞLU N., Cagatay A., Akalin H., Arat M., ...Daha Fazla

TURKISH JOURNAL OF HEMATOLOGY, cilt.31, sa.2, ss.111-120, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 2
  • Basım Tarihi: 2014
  • Doi Numarası: 10.4274/tjh.2014.0103
  • Dergi Adı: TURKISH JOURNAL OF HEMATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.111-120
  • Anahtar Kelimeler: Invasive fungal infection, Antifungal treatment, Evidence, Hematological malignancies, LIPOSOMAL AMPHOTERICIN-B, PREEMPTIVE ANTIFUNGAL THERAPY, NEUTROPENIC PATIENTS, EMPIRICAL-TREATMENT, PERSISTENT FEVER, HIGH-RISK, FEBRILE, AMBISOME, VORICONAZOLE, EFFICACY
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

The introduction of novel antifungal agents for the treatment of invasive fungal disease in hematological malignancies and also changing treatment strategies have had a great impact in managing affected patients. The medical literature includes some important clinical studies that are being used as evidence for guidelines. The problem with these studies and the guidelines is that they are not very easy to interpret, they include controversial issues, and they are not easy to apply to every patient or country. This paper was designed to critically show the main problems associated with these approaches and provide important information that will help Turkish doctors to adopt them in daily clinical practice.