Association between serum neopterin, obesity and daytime sleepiness in patients with obstructive sleep apnea


URSAVAŞ A. , KARADAĞ M. , ORAL H. B. , DEMİRDÖĞEN E. , ORAL H. B. , Ege E.

RESPIRATORY MEDICINE, vol.102, no.8, pp.1193-1197, 2008 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 102 Issue: 8
  • Publication Date: 2008
  • Doi Number: 10.1016/j.rmed.2008.02.019
  • Title of Journal : RESPIRATORY MEDICINE
  • Page Numbers: pp.1193-1197
  • Keywords: obesity, sleep apnea, daytime sleepiness, neopterin, ACUTE CORONARY SYNDROMES, INSULIN-RESISTANCE, ARTERY-DISEASE, RISK-FACTOR, KAPPA-B, THICKNESS, MARKER, SYSTEM

Abstract

Objective: Obesity and obstructive sleep apnea (OSA) and systemic inflammation may interact through biochemical pathways. Neopterin (NP) is a monocyte/macrophage activation marker produced by macrophages in response to interferon-gamma secreted by activated T lymphocytes. This study examines the association between NP, obesity and OSA.