Association between serum neopterin, obesity and daytime sleepiness in patients with obstructive sleep apnea


URSAVAŞ A., KARADAĞ M., ORAL H. B., DEMİRDÖĞEN E., ORAL H. B., Ege E.

RESPIRATORY MEDICINE, vol.102, no.8, pp.1193-1197, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 102 Issue: 8
  • Publication Date: 2008
  • Doi Number: 10.1016/j.rmed.2008.02.019
  • Journal Name: RESPIRATORY MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1193-1197
  • Keywords: obesity, sleep apnea, daytime sleepiness, neopterin, ACUTE CORONARY SYNDROMES, INSULIN-RESISTANCE, ARTERY-DISEASE, RISK-FACTOR, KAPPA-B, THICKNESS, MARKER, SYSTEM
  • Bursa Uludag University Affiliated: Yes

Abstract

Objective: Obesity and obstructive sleep apnea (OSA) and systemic inflammation may interact through biochemical pathways. Neopterin (NP) is a monocyte/macrophage activation marker produced by macrophages in response to interferon-gamma secreted by activated T lymphocytes. This study examines the association between NP, obesity and OSA.