The effectiveness of serum amyloid A for prediction of neonatal cholestasis associated with parenteral nutrition in premature infants

ÖZKAN H., Koksal N., Dogan P., Guney-Varal I., Bagci O., ÖZGÜR T.

TURKISH JOURNAL OF PEDIATRICS, vol.61, no.1, pp.26-33, 2019 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 61 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.24953/turkjped.2019.01.005
  • Journal Name: TURKISH JOURNAL OF PEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.26-33
  • Keywords: parenteral nutrition associated cholestasis, serum amyloid-A, C-reactive protein, procalcitonin, premature infant, C-REACTIVE PROTEIN, LIVER-DISEASE, FOLLOW-UP, NECROTIZING ENTEROCOLITIS, LIPID EMULSIONS, FISH-OIL, PROCALCITONIN, DIAGNOSIS, RISK
  • Bursa Uludag University Affiliated: Yes

Abstract

Parenteral nutrition (PN) has been widely used in premature infants untill enteral feeding can be tolerated. Cholestasis is an important complication of PN. The objective of this study was to evaluate the role of serial measurements of serum amyloid A (SAA) during PN and compare its' effectiveness with C-reactive protein (CRP) and procalcitonin (PCT). We also aimed to determine the risk factors for PN associated cholestasis (PNAC).