Immune reconstitution inflammatory syndrome. A case of postpartum tuberculosis
KLIMIK JOURNAL, vol.19, no.2, pp.79-81, 2006 (ESCI, Scopus)
- Publication Type: Article / Article
- Volume: 19 Issue: 2
- Publication Date: 2006
- Journal Name: KLIMIK JOURNAL
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, Veterinary Science Database
- Page Numbers: pp.79-81
- Keywords: Immune reconstitution inflammatory syndrome, tuberculosis
- Bursa Uludag University Affiliated: Yes
Abstract
Immunorestitution disease or immune reconstitution inflammatory syndrome was initially described in HIV/AIDS patients under antiretroviral therapy. Although there were a decrease in viral load, control of viral replication and an increase in CD4+ T lymphocyte counts, the appearance of different forms of opportunistic infections and deterioration in their clinical status were observed in these patients. This clinical deterioration is a result of an excessive inflammatory response against previously diagnosed or asymptomatic opportunistic pathogens or undefined antigens. Recently, this syndrome was defined in HIV- negative patients and in other cases such as development of paradoxical response during antituberculosis therapy. In this report we present a case with postpartum tuberculosis from the perspective of immunorestitution disease