Immune reconstitution inflammatory syndrome. A case of postpartum tuberculosis

KAZAK E. , Akalin H. , Gurcuoglu E., YILMAZ E. , HEPER Y. , HAKYEMEZ B. , ...More

KLIMIK JOURNAL, vol.19, no.2, pp.79-81, 2006 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 2
  • Publication Date: 2006
  • Title of Journal : KLIMIK JOURNAL
  • Page Numbers: pp.79-81


Immunorestitution disease or immune reconstitution inflammatory syndrome was initially described in HIV/AIDS patients under antiretroviral therapy. Although there were a decrease in viral load, control of viral replication and an increase in CD4+ T lymphocyte counts, the appearance of different forms of opportunistic infections and deterioration in their clinical status were observed in these patients. This clinical deterioration is a result of an excessive inflammatory response against previously diagnosed or asymptomatic opportunistic pathogens or undefined antigens. Recently, this syndrome was defined in HIV- negative patients and in other cases such as development of paradoxical response during antituberculosis therapy. In this report we present a case with postpartum tuberculosis from the perspective of immunorestitution disease