Impact of Genetic Variants in Human Scavenger Receptor Class B Type I (SCARB1) on Plasma Lipid Traits

Niemsiri, Vipavee; Wang, Xingbin; PİRİM, DİLEK; Radwan, Zaheda; Hokanson, John; Hamman, Richard; Barmada, M.; Demirci, F.; Kamboh, M.

doi:10.1161/circgenetics.114.000559

Impact of Genetic Variants in Human Scavenger Receptor Class B Type I (SCARB1) on Plasma Lipid Traits

Niemsiri V., Wang X., PİRİM D., Radwan Z. H., Hokanson J. E., Hamman R. F., ...Daha Fazla

CIRCULATION-CARDIOVASCULAR GENETICS, cilt.7, sa.6, ss.838-898, 2014 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 7 Sayı: 6
Basım Tarihi: 2014
Doi Numarası: 10.1161/circgenetics.114.000559
Dergi Adı: CIRCULATION-CARDIOVASCULAR GENETICS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.838-898
Anahtar Kelimeler: genetic association studies, genetic variation, haplotypes, lipids, polymorphism, genetic, SCARB1 protein, human, sequence analysis, DNA, HIGH-DENSITY-LIPOPROTEIN, HDL-CHOLESTEROL, SR-BI, TRANSGENIC MICE, ASSOCIATION, METABOLISM, APOLIPOPROTEINS, OVEREXPRESSION, DISEASE, RISK
Bursa Uludağ Üniversitesi Adresli: Hayır

Özet

Background-Scavenger receptor class B type 1 (SCARB1) plays an important role in high-density lipoprotein cholesterol (HDL-C) metabolism in selective cholesteryl ester uptake and in free cholesterol cellular efflux.