Localized unilateral hyperhidrosis and neurofibromatosis type 1: Case report of a new association

Baskan E., Karli N., Baykara M., Cikman S., Tunali S.

DERMATOLOGY, vol.211, no.3, pp.286-289, 2005 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 211 Issue: 3
  • Publication Date: 2005
  • Doi Number: 10.1159/000087026
  • Journal Name: DERMATOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.286-289
  • Keywords: localized unilateral hyperhidrosis, neurofibromatosis type 1, botulinum toxin, FEATURES, FACE
  • Bursa Uludag University Affiliated: Yes


Localized unilateral hyperhidrosis (LUH) is an uncommon but well-defined special form of localized hyperhidrosis with diverse causes. It often occurs within a sharply demarcated area on the face or upper extremities. Here, we report a case of LUH in a 16-year-old male with neurofibromatosis type 1 (NF1) and review related data in the literature. The association of this rare entity and NF1 has not yet been described. Subcutaneous botulinum toxin A injection provided a good clinical response with symptomatic relief.