Medical science monitor : international medical journal of experimental and clinical research, vol.15, no.4, 2009 (SCI-Expanded)
Article / Article
Medical science monitor : international medical journal of experimental and clinical research
Science Citation Index Expanded (SCI-EXPANDED), Scopus
nonalcoholic steatohepatitis, chronic hepatitis C, apoptosis, histopathology, biomarker, FATTY LIVER-DISEASE, EXTRACELLULAR CYTOKERATIN-18, SCORING SYSTEM, SOLUBLE FORMS, APOPTOSIS, EXPRESSION, STEATOSIS
Bursa Uludag University Affiliated:
Background: Caspase-cleaved cytokeratin 18 (CK18-Asp396) is released from hepatocytes during apoptosis. Recent studies have indicated that serum levels of CK18-Asp396 could be clinically useful biomarker of chronic liver disease. To shed more light on the rate of hepatocyte loss by apoptosis in chronic liver disease, serum levels of CK18-Asp396 were examined in patients with nonalcoholic steatohepatitis (NASH) and chronic hepatitis C.