High-dose taurine supplementation increases serum paraoxonase and arylesterase activities in experimental hypothyroidism

Dirican M., Tas S., Sarandol E.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, cilt.34, sa.9, ss.833-837, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 9
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1111/j.1440-1681.2007.04615.x
  • Dergi Adı: CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.833-837
  • Anahtar Kelimeler: arylesterase, hypothyroidism, lipid, oxidative stress, paraoxonase, taurine, LOW-DENSITY-LIPOPROTEIN, DIETARY TAURINE, OXIDATIVE STRESS, LIPID-PEROXIDATION, LIVER CHOLESTEROL, RATS, METABOLISM, PLASMA, DEGRADATION, PROTECTION
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Hypothyroidism is accompanied by hyperlipidaemia and oxidative stress and is associated with several complications, such as atherosclerosis. Paraoxonase activity has been reported to decrease in several situations associated with atherosclerosis and oxidative stress. In the present study, the effects of different doses of taurine on serum paraoxonase and arylesterase activities, as well as on the serum lipid profile, were investigated in hypothyroid rats.