A family with IgA nephropathy and hereditary lymphoedema praecox

Usta M., Dilek K., Ersoy A., Alper E., Ozbek S., Ozdemir B., ...More

JOURNAL OF INTERNAL MEDICINE, vol.251, no.5, pp.447-451, 2002 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 251 Issue: 5
  • Publication Date: 2002
  • Doi Number: 10.1046/j.1365-2796.2002.00976.x
  • Journal Name: JOURNAL OF INTERNAL MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.447-451
  • Keywords: hereditary lymphoedema, immunoglobulin A nephropathy, PATHOGENESIS, LYMPHEDEMA
  • Bursa Uludag University Affiliated: Yes

Abstract

Immunoglobulin A (IgA) nephropathy is the most common primary glomerulonephritis worldwide. The pathogenesis is still unknown and treatment has not yet been established. Rarely it can be associated with other disorders. Its association with hereditary lymphoedema is not reported before. We report four patients, a 60-year-old father, his two sons and his daughter, with hereditary lymphoedema. The family had nine members and in four of them lymphoedema was evident. The other members had neither lymphoedema nor IgA nephropathy. This is the first report of IgA nephropathy in association with hereditary lymphoedema.