ACTA NEUROCHIRURGICA, vol.152, no.6, pp.1033-1042, 2010 (SCI-Expanded)
Article / Article
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Apoptosis, Citicoline, Postconditioning, Spinal cord ischemia, CEREBROSPINAL-FLUID DRAINAGE, CDP-CHOLINE, REPERFUSION INJURY, CEREBRAL-ISCHEMIA, THORACOABDOMINAL AORTA, FOCAL ISCHEMIA, CIRCULATORY ARREST, CASPASE ACTIVATION, ANEURYSM REPAIR, BRAIN-DAMAGE
Bursa Uludag University Affiliated:
Ischemic spinal cord injury is a chain of events caused by the reduction and/or cessation of spinal cord blood flow, which results in neuronal degeneration and loss. Ischemic postconditioning is defined as a series of intermittent interruptions of blood flow in the early phase of reperfusion and has been shown to reduce the infarct size in cerebral ischemia. Our study aimed to characterize the relationship between the neuronal injury-decreasing effects of citicoline and ischemic postconditioning, which were proven to be effective against the apoptotic process.