Multidrug-Resistant <i>Campylobacter jejuni</i> Bacteremia Case Following Sheepskin Wrap Application


Akçalı B., Kazak E., Ametoglou Z. C., Öngen Y., Konak Z., Şentürk D. M., ...More

VECTOR-BORNE AND ZOONOTIC DISEASES, vol.26, no.1, pp.57-59, 2026 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 26 Issue: 1
  • Publication Date: 2026
  • Doi Number: 10.1177/15303667251405809
  • Journal Name: VECTOR-BORNE AND ZOONOTIC DISEASES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, Environment Index, MEDLINE
  • Page Numbers: pp.57-59
  • Bursa Uludag University Affiliated: Yes

Abstract

Background: Campylobacter jejuni typically causes gastrointestinal illness but may lead to severe systemic infection in immunocompromised hosts. Resistance to macrolides, fluoroquinolones, and tetracyclines is increasingly reported.Case Presentation: A 27-year-old male with X-linked agammaglobulinemia developed recurrent right foot cellulitis after local trauma. Following application of a non-sterile herbal ointment and sheepskin, the lesion progressed, and the patient developed fever and chills. Blood cultures repeatedly yielded multidrug-resistant C. jejuni, while wound culture grew Citrobacter braakii. The C. jejuni isolates showed high MICs to macrolides, fluoroquinolones, and tetracycline. Given persistent bacteremia despite broad-spectrum therapy, meropenem was initiated, resulting in rapid defervescence and clinical improvement.Conclusion: This case highlights the potential for transdermal acquisition of C. jejuni in immunodeficient patients, the clinical challenges posed by multidrug-resistant strains, and the need for education regarding traditional practices that may increase infection risk.