Effect of Minimally Invasive Surfactant Therapy vs Sham Treatment on Death or Bronchopulmonary Dysplasia in Preterm Infants With Respiratory Distress Syndrome: The OPTIMIST-A Randomized Clinical Trial.

Dargaville P. A. , Kamlin C. O. F. , Orsini F., Wang X., De Paoli A. G. , Kanmaz Kutman H. G. , ...More

JAMA, vol.326, pp.2478-2487, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 326
  • Publication Date: 2021
  • Doi Number: 10.1001/jama.2021.21892
  • Title of Journal : JAMA
  • Page Numbers: pp.2478-2487


IMPORTANCE The benefits of surfactant administration via a thin catheter (minimally invasive surfactant therapy [MIST]) in preterm infants with respiratory distress syndrome are uncertain.