Effect of Minimally Invasive Surfactant Therapy vs Sham Treatment on Death or Bronchopulmonary Dysplasia in Preterm Infants With Respiratory Distress Syndrome: The OPTIMIST-A Randomized Clinical Trial.

Dargaville, Peter; Kamlin, C; Orsini, Francesca; Wang, Xiaofang; De Paoli, Antonio; Kanmaz Kutman, H; Cetinkaya, Merih; Kornhauser-Cerar, Lilijana; Derrick, Matthew; Özkan, HİLAL; Hulzebos, Christian; Schmölzer, Georg; Aiyappan, Ajit; Lemyre, Brigitte; Kuo, Sheree; Rajadurai, Victor; O'Shea, Joyce; Biniwale, Manoj; Ramanathan, Rangasamy; Kushnir, Alla; Bader, David; Thomas, Mark; Chakraborty, Mallinath; Buksh, Mariam; Bhatia, Risha; Sullivan, Carol; Shinwell, Eric; Dyson, Amanda; Barker, David; Kugelman, Amir; Donovan, Tim; Tauscher, Markus; Murthy, Vadivelam; Ali, Sanoj; Yossuck, Pete; Clark, Howard; Soll, Roger; Carlin, John; Davis, Peter

doi:10.1001/jama.2021.21892

Effect of Minimally Invasive Surfactant Therapy vs Sham Treatment on Death or Bronchopulmonary Dysplasia in Preterm Infants With Respiratory Distress Syndrome: The OPTIMIST-A Randomized Clinical Trial.

Dargaville P. A. , Kamlin C. O. F. , Orsini F., Wang X., De Paoli A. G. , Kanmaz Kutman H. G. , ...More

JAMA, vol.326, pp.2478-2487, 2021 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 326
Publication Date: 2021
Doi Number: 10.1001/jama.2021.21892
Title of Journal : JAMA
Page Numbers: pp.2478-2487

Abstract

IMPORTANCE The benefits of surfactant administration via a thin catheter (minimally invasive surfactant therapy [MIST]) in preterm infants with respiratory distress syndrome are uncertain.