Serum pigment epithelium-derived factor levels are increased in patients with biopsy-proven nonalcoholic fatty liver disease and independently associated with liver steatosis.

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YILMAZ Y., EREN F., Ayyildiz T., Colak Y., Kurt R., Senates E., ...More

Clinica chimica acta; international journal of clinical chemistry, vol.412, pp.2296-9, 2011 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 412
• Publication Date: 2011
• Doi Number: 10.1016/j.cca.2011.08.025
• Journal Name: Clinica chimica acta; international journal of clinical chemistry
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.2296-9
• Bursa Uludag University Affiliated: Yes

Abstract

Background: Increased serum concentrations of pigment epithelium-derived factor (PEDF) have been linked to the metabolic syndrome in the general population. However, the relationship between serum PEDF and nonalcoholic fatty liver disease (NAFLD), a hepatic manifestation of the metabolic syndrome, remains unknown.