Serum pigment epithelium-derived factor levels are increased in patients with biopsy-proven nonalcoholic fatty liver disease and independently associated with liver steatosis.

YILMAZ Y., EREN F., Ayyildiz T., Colak Y., Kurt R., Senates E., ...More

Clinica chimica acta; international journal of clinical chemistry, vol.412, pp.2296-9, 2011 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 412
  • Publication Date: 2011
  • Doi Number: 10.1016/j.cca.2011.08.025
  • Title of Journal : Clinica chimica acta; international journal of clinical chemistry
  • Page Numbers: pp.2296-9


Background: Increased serum concentrations of pigment epithelium-derived factor (PEDF) have been linked to the metabolic syndrome in the general population. However, the relationship between serum PEDF and nonalcoholic fatty liver disease (NAFLD), a hepatic manifestation of the metabolic syndrome, remains unknown.