Effects of hypoxic preconditioning in antioxidant enzyme activities in hypoxic-ischemic brain damage in immature rats.


Alkan T., GÖREN B., Vatansever E., SARANDÖL E.

Turkish neurosurgery, vol.18, no.2, pp.165-71, 2008 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18 Issue: 2
  • Publication Date: 2008
  • Journal Name: Turkish neurosurgery
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.165-71
  • Keywords: antioxidant enzymes, hypoxic ischemic brain damage, lipid peroxidation, neuroprotection, preconditioning, NEONATAL-RAT, LIPID-PEROXIDATION, TOLERANCE, NEUROPROTECTION, PROTECTION, MECHANISM, INJURY

Abstract

AIM: HI (hypoxic-ischemic) brain injury is a major cause of neonatal mortality and long-term neurological morbidity. The aim of the present study was to investigate the effects of HPC (hypoxic preconditioning) on the oxidative-antioxidative status in the neonatal HI brain model.