Preclinical safety evaluation of intravitreal injection of full-length humanized vascular endothelial growth factor antibody in rabbit eyes.

Inan U. U. , Avci B., Kusbeci T., Kaderli B., Avci R., Temel Ş. G.

Investigative ophthalmology & visual science, vol.48, no.4, pp.1773-81, 2007 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 48 Issue: 4
  • Publication Date: 2007
  • Doi Number: 10.1167/iovs.06-0828
  • Journal Name: Investigative ophthalmology & visual science
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.1773-81


PURPOSE. To evaluate the preclinical safety of intravitreal bevacizumab, which is a full-length humanized monoclonal antibody against the vascular endothelial growth factor (VEGF), in rabbit eves over a short-term period.