Preclinical safety evaluation of intravitreal injection of full-length humanized vascular endothelial growth factor antibody in rabbit eyes.

Inan, Umit; Avci, BERRİN; Kusbeci, Tuncay; Kaderli, Berkant; Avci, Remzi; Temel, ŞEHİME

doi:10.1167/iovs.06-0828

Preclinical safety evaluation of intravitreal injection of full-length humanized vascular endothelial growth factor antibody in rabbit eyes.

Inan U. U., Avci B., Kusbeci T., Kaderli B., Avci R., Temel Ş. G.

Investigative ophthalmology & visual science, cilt.48, sa.4, ss.1773-81, 2007 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 48 Sayı: 4
Basım Tarihi: 2007
Doi Numarası: 10.1167/iovs.06-0828
Dergi Adı: Investigative ophthalmology & visual science
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1773-81
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

PURPOSE. To evaluate the preclinical safety of intravitreal bevacizumab, which is a full-length humanized monoclonal antibody against the vascular endothelial growth factor (VEGF), in rabbit eves over a short-term period.