Preclinical safety evaluation of intravitreal injection of full-length humanized vascular endothelial growth factor antibody in rabbit eyes.


Inan U. U., Avci B., Kusbeci T., Kaderli B., Avci R., Temel Ş. G.

Investigative ophthalmology & visual science, vol.48, no.4, pp.1773-81, 2007 (SCI-Expanded) identifier identifier identifier

Abstract

PURPOSE. To evaluate the preclinical safety of intravitreal bevacizumab, which is a full-length humanized monoclonal antibody against the vascular endothelial growth factor (VEGF), in rabbit eves over a short-term period.