Akademik Veri Yönetim Sistemi
CUKUROVA MEDICAL JOURNAL, cilt.44, 2019 (ESCI)
Purpose: Snake venom has serious cardiotoxic, neurotoxic, nephrotoxic effects. The neutrophil-to-lymphocyte ratio (NLR) is a new biomarker of inflammation and can be used as an indicator and prognositic marker of inflammation. In this study we aimed to analyze the association with clinical outcomes of pediatric patients with snakebite envenomation, and NLR. Materials and Methods: A total of 61 pediatric patients with snakebite who admitted to a tertiary university hospital and a children's hospital between July 2012 and July 2017 were included in the study. Demographic features, clinical findings and complications of snakebite, length of stay in hospital, NLR at admission (NLR1), and NLR at the twelfth hour (NLR2) and NLR at the discharge (NLR3) and mean platelet volume (MPV) were retrospectively reviewed and recorded. Results: There was a positive correlation between NLR1 and the length of hospital stay. We found that as the level of NLR1 increased, the length of hospitalization was prolonged. NLR1 level increased as the disease stage progressed, but it was not statistically significant. Our study showed that when the severity of the illness increased, the length of hospital stay was significantly prolonged. Conclusion: The study revealed a positive correlation with NLR and severity of the illness. We claim that NLR at admission can be a useful marker for predicting severe clinical course and prolonged hospital length of stay for pediatric patients with snake envenomation.