ANNALS OF THE AMERICAN THORACIC SOCIETY, cilt.16, sa.12, ss.1504-1517, 2019 (SCI-Expanded)
Rationale: A positive bronchodilator response (BDR) according to American Thoracic Society/European Respiratory Society (ATS/ERS) guidelines require both 200 ml and 12% increase in forced expiratory volume in 1 second (FEV1) or forced vital capacity (FVC) after bronchodilator inhalation. This dual criterion is insensitive in those with high or low FEV1.