A New Bronchodilator Response Grading Strategy Identifies Distinct Patient Populations


Hansen J. E. , Dilektasli A. G. , Porszasz J., Stringer W. W. , Pak Y., Rossiter H. B. , ...More

ANNALS OF THE AMERICAN THORACIC SOCIETY, vol.16, no.12, pp.1504-1517, 2019 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 12
  • Publication Date: 2019
  • Doi Number: 10.1513/annalsats.201901-030oc
  • Title of Journal : ANNALS OF THE AMERICAN THORACIC SOCIETY
  • Page Numbers: pp.1504-1517

Abstract

Rationale: A positive bronchodilator response (BDR) according to American Thoracic Society/European Respiratory Society (ATS/ERS) guidelines require both 200 ml and 12% increase in forced expiratory volume in 1 second (FEV1) or forced vital capacity (FVC) after bronchodilator inhalation. This dual criterion is insensitive in those with high or low FEV1.