Prognostic impact of tumor lymphocytic infiltrates in patients with breast cancer undergoing neoadjuvant chemotherapy

Avci N., DELİGÖNÜL A. , TOLUNAY Ş. , Cubukcu E. , Olmez O. F. , Altmisdortoglu O., ...More

JOURNAL OF BUON, vol.20, no.4, pp.994-1000, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 4
  • Publication Date: 2015
  • Title of Journal : JOURNAL OF BUON
  • Page Numbers: pp.994-1000
  • Keywords: breast cancer, neoadjuvant chemotherapy, prognosis, tumor lymphocytic infiltrates, IMMUNE CELLS, INFLAMMATION, SURVIVAL


Purpose: The presence of a pronounced tumor lymphocytic infiltrate (TLI) is deemed to reflect the presence of an immunoinflammatory response against the tumor and may thus have prognostic significance. We investigated the prognostic value of TLI detected in pathological specimens collected following neoadjuvant chemotherapy (NACT) in patients with breast cancer.