Prognostic impact of tumor lymphocytic infiltrates in patients with breast cancer undergoing neoadjuvant chemotherapy


Avci N., DELİGÖNÜL A., TOLUNAY Ş., Cubukcu E., Olmez O. F., Altmisdortoglu O., ...Daha Fazla

JOURNAL OF BUON, cilt.20, sa.4, ss.994-1000, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20 Sayı: 4
  • Basım Tarihi: 2015
  • Dergi Adı: JOURNAL OF BUON
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.994-1000
  • Anahtar Kelimeler: breast cancer, neoadjuvant chemotherapy, prognosis, tumor lymphocytic infiltrates, IMMUNE CELLS, INFLAMMATION, SURVIVAL
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Purpose: The presence of a pronounced tumor lymphocytic infiltrate (TLI) is deemed to reflect the presence of an immunoinflammatory response against the tumor and may thus have prognostic significance. We investigated the prognostic value of TLI detected in pathological specimens collected following neoadjuvant chemotherapy (NACT) in patients with breast cancer.