Prognostic impact of tumor lymphocytic infiltrates in patients with breast cancer undergoing neoadjuvant chemotherapy

Avci N., DELİGÖNÜL A., TOLUNAY Ş., Cubukcu E., Olmez O. F., Altmisdortoglu O., ...More

JOURNAL OF BUON, vol.20, no.4, pp.994-1000, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 4
  • Publication Date: 2015
  • Journal Name: JOURNAL OF BUON
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.994-1000
  • Keywords: breast cancer, neoadjuvant chemotherapy, prognosis, tumor lymphocytic infiltrates, IMMUNE CELLS, INFLAMMATION, SURVIVAL
  • Bursa Uludag University Affiliated: Yes

Abstract

Purpose: The presence of a pronounced tumor lymphocytic infiltrate (TLI) is deemed to reflect the presence of an immunoinflammatory response against the tumor and may thus have prognostic significance. We investigated the prognostic value of TLI detected in pathological specimens collected following neoadjuvant chemotherapy (NACT) in patients with breast cancer.