Preclinical evidence for the antihyperalgesic activity of CDP-choline in oxaliplatin-induced neuropathic pain

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Kanat O., Bagdas D., Ozboluk H. Y., Gurun M. S.

JOURNAL OF BUON, vol.18, no.4, pp.1012-1018, 2013 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 18 Issue: 4
• Publication Date: 2013
• Journal Name: JOURNAL OF BUON
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.1012-1018
• Keywords: CDP-choline, neuropathy, oxaliplatin, pain, INFLAMMATORY PAIN, ANTICANCER AGENT, MODEL, RAT, CHANNELS, INJECTION, CANCER, NA+
• Bursa Uludag University Affiliated: Yes

Abstract

Purpose: This study was designed to evaluate the antihyperalgesic effect of CDP-choline (cytidine-5'-diphosphate-choline; citicoline) in a rat model of neuropathic pain produced by oxaliplatin (OXA).