Preclinical evidence for the antihyperalgesic activity of CDP-choline in oxaliplatin-induced neuropathic pain

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Kanat O., Bagdas D., Ozboluk H. Y., Gurun M. S.

JOURNAL OF BUON, cilt.18, sa.4, ss.1012-1018, 2013 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 18 Sayı: 4
• Basım Tarihi: 2013
• Dergi Adı: JOURNAL OF BUON
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.1012-1018
• Anahtar Kelimeler: CDP-choline, neuropathy, oxaliplatin, pain, INFLAMMATORY PAIN, ANTICANCER AGENT, MODEL, RAT, CHANNELS, INJECTION, CANCER, NA+
• Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Purpose: This study was designed to evaluate the antihyperalgesic effect of CDP-choline (cytidine-5'-diphosphate-choline; citicoline) in a rat model of neuropathic pain produced by oxaliplatin (OXA).