Transient hepatitis B surface antigenemia after neonatal hepatitis B immunization

Koksal N., Altinkaya N., Perk Y.

ACTA PAEDIATRICA, vol.85, no.12, pp.1501-1502, 1996 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 85 Issue: 12
  • Publication Date: 1996
  • Doi Number: 10.1111/j.1651-2227.1996.tb13961.x
  • Journal Name: ACTA PAEDIATRICA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1501-1502
  • Keywords: HBsAg antigenemia, hepatitis vaccine, newborn, IMMUNOGENICITY, VACCINE, SAFETY
  • Bursa Uludag University Affiliated: Yes


Following immunization with hepatitis B vaccine, 39 infants were followed prospectively for hepatitis B surface antigen (HBsAg). A total of 69.2% of the infants tested positive for antigenemia at least once. Antigenemia was identified most often at 2-3 days (43.5%) and 5-6 days (43.5%) after immunization. The longest documented duration of antigenemia was 21 days. In all cases the antigenemia was transient and cleared by the 28th day post-vaccination.