Retrospective Evaluation of Colistin-Resistant Isolates in Automated System by Gradient Diffusion Method and Broth Microdilution Method

Tüzemen N. Ü., Efe K., Akalin H., Özakın C.

KLIMIK JOURNAL, vol.32, no.1, pp.57-61, 2019 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.5152/kd.2019.13
  • Journal Name: KLIMIK JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.57-61
  • Keywords: Colistin, antibiotic susceptibility testing, drug resistance, SUSCEPTIBILITY TESTING METHODS, AGAR DILUTION, DISC DIFFUSION, ANTIMICROBIAL ACTIVITY, VITEK 2, ETEST, TIGECYCLINE, PNEUMONIAE, MECHANISMS, MICROSCAN
  • Bursa Uludag University Affiliated: Yes

Abstract

Objective: Optimizing colistin susceptibility testing has difficulties because of its high molecular weight and high binding capacity to polystyrene which is frequently used in antibiotic susceptibility testing. We aimed to compare the results of isolates, which were detected as colistin-resistant in the automated system, obtained by using broth microdilution (BMD) method which is the gold standard, with gradient diffusion method (GDM).