PAKISTAN JOURNAL OF STATISTICS, vol.26, no.4, pp.659-671, 2010 (SCI-Expanded)
Article / Article
PAKISTAN JOURNAL OF STATISTICS
Science Citation Index Expanded (SCI-EXPANDED), Scopus
ROC curve, Time-dependent ROC, Cut-off, Ki67, OPERATING CHARACTERISTIC CURVES, S-PHASE FRACTION, BREAST-CANCER, MEASUREMENT ERROR, PROGNOSTIC VALUE, YOUDEN INDEX, KI-67, MARKERS, AREA, METHODOLOGY
Bursa Uludag University Affiliated:
Receiver operating characteristic (ROC) curve is one of the most active research areas in medical statistics. While classic ROC curve analysis is a well-established method to study the accuracies of clinical markers, it may be suboptimal for analyzing outcomes over time, such as prognosis. When the outcome variable of interest is an event that occurs not concurrent with the tests, time-dependent ROC curves should be used to accommodate this time lag.