Association of TNF-alpha-308 polymorphism with the outcome of hepatitis B virus infection in Turkey


Basturk B., KARASU A. Z. , KILIÇ M., ULUKAYA S., Boyacioglu S., ORAL H. B.

INFECTION GENETICS AND EVOLUTION, vol.8, no.1, pp.20-25, 2008 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 1
  • Publication Date: 2008
  • Doi Number: 10.1016/j.meegid.2007.09.001
  • Title of Journal : INFECTION GENETICS AND EVOLUTION
  • Page Numbers: pp.20-25
  • Keywords: cytokines, gene polymorphisms, hepatic failure, hepatitis B, NECROSIS-FACTOR-ALPHA, INTERLEUKIN-10 GENE PROMOTER, ALLELE FREQUENCIES, T-CELLS, CLEARANCE, CYTOKINES, SURFACE, PROGRESSION, POPULATION, TGF-BETA-1

Abstract

Background and aim: Cytokines play important roles in the regulation of immune response. The aim of the study was to investigate the association of the cytokine gene polymorphisms with persistence of hepatitis B virus (HBV) infection and the development of end-stage liver disease (ESLD) due to HBV infection.