Association of TNF-alpha-308 polymorphism with the outcome of hepatitis B virus infection in Turkey

Basturk, Bilkay; KARASU, ABDULLAH; KILIÇ, MURAT; ULUKAYA, SEZGİN; Boyacioglu, Sedat; ORAL, HALUK

doi:10.1016/j.meegid.2007.09.001

Association of TNF-alpha-308 polymorphism with the outcome of hepatitis B virus infection in Turkey

Basturk B., KARASU A. Z., KILIÇ M., ULUKAYA S., Boyacioglu S., ORAL H. B.

INFECTION GENETICS AND EVOLUTION, cilt.8, sa.1, ss.20-25, 2008 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 8 Sayı: 1
Basım Tarihi: 2008
Doi Numarası: 10.1016/j.meegid.2007.09.001
Dergi Adı: INFECTION GENETICS AND EVOLUTION
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.20-25
Anahtar Kelimeler: cytokines, gene polymorphisms, hepatic failure, hepatitis B, NECROSIS-FACTOR-ALPHA, INTERLEUKIN-10 GENE PROMOTER, ALLELE FREQUENCIES, T-CELLS, CLEARANCE, CYTOKINES, SURFACE, PROGRESSION, POPULATION, TGF-BETA-1
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Background and aim: Cytokines play important roles in the regulation of immune response. The aim of the study was to investigate the association of the cytokine gene polymorphisms with persistence of hepatitis B virus (HBV) infection and the development of end-stage liver disease (ESLD) due to HBV infection.