The effect of topical 5-fluorouracil application on epineural scar tissue in epineurectomized rat sciatic nerve

Cavus Ozkan M., Tuncel B., ÖZGENEL G. Y.

MARMARA MEDICAL JOURNAL, vol.31, no.1, pp.1-10, 2018 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.5472/marumj.342046
  • Journal Name: MARMARA MEDICAL JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1-10
  • Bursa Uludag University Affiliated: Yes

Abstract

Objective: This study investigated the effect of topical 5-fluorouracil (5-FU) application on the epineural scar tissue, which has a negative impact on the outcome after a peripheral nerve surgery, and whether the application of two doses of 5-FU would change the outcome.