MicroRNA expression patterns of tumors in early-onset colorectal cancer patients.

Ak S., TUNCA B., Tezcan G., ÇEÇENER G., EGELİ Ü., Yilmazlar T., ...Daha Fazla

The Journal of surgical research, cilt.191, sa.1, ss.113-22, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 191 Sayı: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1016/j.jss.2014.03.057
  • Dergi Adı: The Journal of surgical research
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.113-22
  • Anahtar Kelimeler: miR-106a, miR-125b, miR-143, Colorectal cancer, Early onset, AFRICAN-AMERICAN, PROGNOSIS, PROFILES, BIOMARKERS, DIFFERENTIATION, SIGNATURE, CARCINOMA, DIAGNOSIS, MIR-125B, INVASION
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Background: The expression of microRNAs (miRNAs) may differ in tumors from patients with different ethnic origins and ages. The aims of the present study were to clarify the appropriate alterations of miRNA expression associated with the early stages of carcinogenesis in early-onset Turkish colorectal cancer (CRC) patients and to define specific biomarkers that could be used as new diagnostic and prognostic markers for this population.