MicroRNA expression patterns of tumors in early-onset colorectal cancer patients.

Ak S., TUNCA B., Tezcan G., ÇEÇENER G., EGELİ Ü., Yilmazlar T., ...More

The Journal of surgical research, vol.191, no.1, pp.113-22, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 191 Issue: 1
  • Publication Date: 2014
  • Doi Number: 10.1016/j.jss.2014.03.057
  • Journal Name: The Journal of surgical research
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.113-22
  • Keywords: miR-106a, miR-125b, miR-143, Colorectal cancer, Early onset, AFRICAN-AMERICAN, PROGNOSIS, PROFILES, BIOMARKERS, DIFFERENTIATION, SIGNATURE, CARCINOMA, DIAGNOSIS, MIR-125B, INVASION
  • Bursa Uludag University Affiliated: Yes

Abstract

Background: The expression of microRNAs (miRNAs) may differ in tumors from patients with different ethnic origins and ages. The aims of the present study were to clarify the appropriate alterations of miRNA expression associated with the early stages of carcinogenesis in early-onset Turkish colorectal cancer (CRC) patients and to define specific biomarkers that could be used as new diagnostic and prognostic markers for this population.