Additional cytogenetic abnormalities and variant t(9;22) at the diagnosis of childhood chronic myeloid leukemia: The experience of the International Registry for Chronic Myeloid Leukemia in Children and Adolescents

Millot F., Dupraz C., Guilhot J., Suttorp M., Brizard F., Leblanc T., ...Daha Fazla

CANCER, cilt.123, sa.18, ss.3609-3616, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 123 Sayı: 18
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1002/cncr.30767
  • Dergi Adı: CANCER
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.3609-3616
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

BACKGROUNDIn the adult population with newly diagnosed chronic myeloid leukemia (CML), variant translocations are usually not considered to be impairing the prognosis, whereas some additional cytogenetic abnormalities (ACAs) are associated with a negative impact on survival. Because of the rarity of CML in the pediatric population, such abnormalities have not been investigated in a large group of children with CML.