Cerebellar volume in early-onset schizophrenia and its association with severity of symptoms


Ozbek A., Mas N. G. , Turan S., Ay B., Demirgoren B. S. , DEMİRCİ G. N. , ...More

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, vol.47, no.1, pp.411-419, 2019 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 47 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.1177/0300060518803028
  • Journal Name: JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.411-419
  • Keywords: Early-onset schizophrenia, cerebellum, stereology, magnetic resonance imaging, Positive and Negative Syndrome Scale (PANSS), general functionality, BRAIN ABNORMALITIES, ASYMMETRIES, MRI

Abstract

Objectives This study aimed to investigate whether early-onset schizophrenia (EOS) cases differ from controls regarding volumes of the total cerebellum and the right and left cerebellar hemispheres, and volumetric asymmetry. Correlations of cerebellar volumes and asymmetry indices with severity of symptoms and general functioning in cases of EOS were also assessed.