Investigation of Neuroprotective Effects of Cyclooxygenase Inhibitors in the 6-Hydroxydopamine Induced Rat Parkinson Model

Gören B., Mimbay Z. , Bilici N., Zarifoğlu M. , Ogul E., Korfali E.

TURKISH NEUROSURGERY, vol.19, pp.230-236, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19
  • Publication Date: 2009
  • Title of Journal : TURKISH NEUROSURGERY
  • Page Numbers: pp.230-236


AIM: Recent experimental and clinical studies on Parkinson's disease point out the pivotal role of inflammation in the pathogenesis of neurodegeneration and the possible positive effects of nonsteroidal anti-inflammatory drug therapies. Our aim in this study was to investigate the preventive effects of nonsteroidal anti-inflammatory drugs in the 6-hydroxydopamine (6-OHDA) induced rat model of Parkinson's disease.