INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, cilt.14, sa.3, ss.276-281, 2011 (SCI-Expanded)
Aim: Raynaud's phenomenon (RP) commonly co-exists with systemic lupus erythematosus (SLE). The obvious pathophysiological mechanism in RP is vasoconstriction. Although the roles of certain vasoconstrictor substances, like endothelin-1, have been identified in RP, underlying mechanisms remain unclear.