Increased urotensin-II activity in patients with Raynaud's phenomenon and systemic lupus erythematosus

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Buyukhatipoglu H., Buyukaslan H., Pehlivan Y., Ceylan N., Ulas T., Tarakcioglu M., ...More

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, vol.14, no.3, pp.276-281, 2011 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 14 Issue: 3
• Publication Date: 2011
• Doi Number: 10.1111/j.1756-185x.2011.01597.x
• Journal Name: INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.276-281
• Bursa Uludag University Affiliated: No

Abstract

Aim: Raynaud's phenomenon (RP) commonly co-exists with systemic lupus erythematosus (SLE). The obvious pathophysiological mechanism in RP is vasoconstriction. Although the roles of certain vasoconstrictor substances, like endothelin-1, have been identified in RP, underlying mechanisms remain unclear.