Increased urotensin-II activity in patients with Raynaud's phenomenon and systemic lupus erythematosus

Buyukhatipoglu H., Buyukaslan H., Pehlivan Y., Ceylan N., Ulas T., Tarakcioglu M., ...More

INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES, vol.14, no.3, pp.276-281, 2011 (SCI-Expanded) identifier identifier identifier


Aim: Raynaud's phenomenon (RP) commonly co-exists with systemic lupus erythematosus (SLE). The obvious pathophysiological mechanism in RP is vasoconstriction. Although the roles of certain vasoconstrictor substances, like endothelin-1, have been identified in RP, underlying mechanisms remain unclear.