Metallic magnesium: an efficient catalyst toward N-aryl and N-alkyl substituted amides directly from aliphatic carboxylic acids


Yildirim A.

MONATSHEFTE FUR CHEMIE, vol.146, no.6, pp.947-951, 2015 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 146 Issue: 6
  • Publication Date: 2015
  • Doi Number: 10.1007/s00706-014-1387-2
  • Journal Name: MONATSHEFTE FUR CHEMIE
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.947-951
  • Keywords: Direct amidation, Amines, Carboxylic acids, Catalysis, Magnesium, ONE-POT, AMINES, CONVERSION, ESTERS, AMIDATION, ANILIDES, SURFACTANTS, ACYLATION, REAGENT

Abstract

An efficient and inexpensive procedure for direct conversion of aliphatic carboxylic acids into amides has been developed using anilines or aliphatic amines and Mg(0) as catalyst in toluene. The amides were obtained by single crystallization in moderate to excellent yields with high purity.