Effect of indomethacin and selective cyclooxygenase-2 inhibitors on proteinuria and renal function in patients with AA type renal amyloidosis
NEPHROLOGY, vol.11, no.3, pp.232-237, 2006 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 11 Issue: 3
- Publication Date: 2006
- Doi Number: 10.1111/j.1440-1797.2006.00562.x
- Journal Name: NEPHROLOGY
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.232-237
- Keywords: amyloidosis, celecoxib, cyclooxygenase-2, non-steroidal anti-inflammatory drugs, proteinuria, rofecoxib, GASTROINTESTINAL TOXICITY, CARDIOVASCULAR EVENTS, RHEUMATOID-ARTHRITIS, NEPHROTIC SYNDROME, COX-2 INHIBITORS, ROFECOXIB, RESOLUTION, CELECOXIB, NAPROXEN, RISK
- Bursa Uludag University Affiliated: Yes
Abstract
Aims: Because the cardiovascular system (CVS) side-effects of cyclooxygenase-2 (COX-2) selective inhibitors have recently been questioned, we aimed to compare the renal and haemodynamic effects of cyclooxygenase selective (celecoxib and rofecoxib) and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) (indomethacin) in patients with renal amyloidosis secondary to rheumatological diseases who required anti-inflammatory agents and are taking maximum tolerable dose of angiotensin-converting enzyme inhibitors.