The potential relationship between QTc interval prolongation and ziprasidone treatment: three cases


Eker S. S. , Sarandol A., Akkaya C., Sivrioglu E. Y. , Kirli S.

JOURNAL OF PSYCHOPHARMACOLOGY, vol.23, no.8, pp.993-996, 2009 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 8
  • Publication Date: 2009
  • Doi Number: 10.1177/0269881108093843
  • Journal Name: JOURNAL OF PSYCHOPHARMACOLOGY
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.993-996

Abstract

QTc interval prolongation may appear as a consequence of both typical and atypical antipsychotic treatments. Ziprasidone, which is effective in treating schizophrenia, is associated with QTc prolongation. Although the prolongation of QTc with ziprasidone treatment is often pronounced, there is a scarce number of cases reported about the relationship between ziprasidone and QTc prolongation. Of the three cases presented in this case series, two cases showed values exceeding 0.50 s with ziprasidone treatment.