Predicting response to peginterferon alpha-2a, lamivudine and the two combined for HBeAg-negative chronic hepatitis B

Bonino, F.; Marcellin, P.; Lau, G.; Hadziyannis, S.; Jin, R.; Piratvisuth, T.; Germanidis, G.; Yurdaydin, C.; Diago, M.; Gurel, SELİM; Lai, M-Y; Brunetto, M.; Farci, P.; Popescu, M.; McCloud, P.

doi:10.1136/gut.2005.089722

Predicting response to peginterferon alpha-2a, lamivudine and the two combined for HBeAg-negative chronic hepatitis B

Atıf İçin Kopyala

Bonino F., Marcellin P., Lau G. K. K., Hadziyannis S., Jin R., Piratvisuth T., ...Daha Fazla

GUT, cilt.56, sa.5, ss.699-705, 2007 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 56 Sayı: 5
Basım Tarihi: 2007
Doi Numarası: 10.1136/gut.2005.089722
Dergi Adı: GUT
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.699-705
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Objective: In a trial of patients with hepatitis B e antigen (HBeAg)-negative chronic hepatitis B, 24 week post-treatment biochemical and virological response rates with peginterferon alpha-2a with or without lamivudine were significantly higher than with lamivudine alone. The effect of pre-treatment factors on post-treatment responses was investigated.