Predicting response to peginterferon alpha-2a, lamivudine and the two combined for HBeAg-negative chronic hepatitis B

Bonino F., Marcellin P., Lau G. K. K., Hadziyannis S., Jin R., Piratvisuth T., ...More

GUT, vol.56, no.5, pp.699-705, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 5
  • Publication Date: 2007
  • Doi Number: 10.1136/gut.2005.089722
  • Journal Name: GUT
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.699-705
  • Bursa Uludag University Affiliated: Yes

Abstract

Objective: In a trial of patients with hepatitis B e antigen (HBeAg)-negative chronic hepatitis B, 24 week post-treatment biochemical and virological response rates with peginterferon alpha-2a with or without lamivudine were significantly higher than with lamivudine alone. The effect of pre-treatment factors on post-treatment responses was investigated.