Malignant fibrous histiocytoma (giant cell type) of soft parts in the abdominal mammary region of a female Ankara (Angora) cat

ÖZYİĞİT M. Ö. , NAK D. , YILMAZ R., NAK Y. , Simsek G.

TURKISH JOURNAL OF VETERINARY & ANIMAL SCIENCES, vol.34, no.5, pp.471-475, 2010 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 5
  • Publication Date: 2010
  • Doi Number: 10.3906/vet-0905-39
  • Page Numbers: pp.471-475


The present report describes a giant cell type of malignant fibrous histiocytoma (MFH), diagnosed in soft parts of the right abdominal mammary region, in an 11-year old, 8 kg, nulliparous female Ankara (Angora) cat diagnosed in soft parts of the right abdominal mammary region. The tumor, surgically excised from the abdominal region, had a flexible consistency with ulcerated overlying skin. The tumor was elliptical (8.0 cm x 7.0 cm x 5.0 cm) with a necrotic area of 3.0 cm x 1.5 cm x 1.0 cm in the middle of the cut surface. Microscopically, the tumor was subcutaneous and unencapsulated. Tumor cells were comprised of a mixture of fibroblast-like spindle and histiocytic-like cells with a pale pink cytoplasm. Cells were oval or elongated with a round, large nucleus, and small single nucleoli. In addition, an abundant number of multi-nucleated giant cells were observed. In some fields, there was a dense collagen connective tissue, foci of cartilaginous, bony metaplasia, and hemorrhage surrounding necrosis.