Hepatitis A seropositivity: comparative results of two hospitals in Turkey

Agca H., Toklu G. D.

JOURNAL OF CLINICAL AND ANALYTICAL MEDICINE, vol.4, no.2, pp.104-106, 2013 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 4 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.4328/jcam.930
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.104-106
  • Bursa Uludag University Affiliated: Yes


Aim: Hepatitis A virus (HAV) is a ribonucleic acid (RNA) picornavirus transmitted by fecal-oral route. HAV is usually silent or subclinic in children and on a worldwide scale only 5 % of infections are recognised clinically. In this study we aimed to determine the seroprevalance of HAV seropositivity in two different hospitals in the Aegean region of Turkey. Material and Method: Serum samples, which were taken from patients to investigate hepatitis A antibodies administrated to Usak State Hospital and Tavsanli Doc. Dr. M. Kalemli State Hospital between January 2011 and December 2011 were investigated for hepatitis A seropositivity retrospectively. Age, sex, Anti HAV Ig G and Anti HAV Ig M were investigated. Results: 799 patients in Usak State Hospital and 461 patients in Tavsanli State hospital were investigated for Anti HAV Ig G and Anti HAV Ig M. 78 % were female, 22 % were male and mean age was 27,7 in Usak State Hospital. 54 % were female, 46 % were male, mean age was 38,0 in Tavsanli State Hospital. Anti-HAV Ig M positivity in Usak and Tavsanli State Hospital are 1,3 % and 0,6 % respectively. Anti-HAV Ig G positivity in Usak and Tavsanli State Hospital are 75,5 % and 80,4 % respectively. Discussion: Improvement of public and individual hygiene, education about hygiene, improvement of education and socioeconomic level of public and vaccination against HAV as recommended by the World Health Organisation may decrease the burden of HAV infection.