Evaluation of DNA damage using the comet assay in children on long-term benzathine penicillin for secondary prophylaxis of rheumatic fever

Dundaroz, R; Ulucan, H; Denli, M; Karapinar, K; Aydin, HI; Baltaci, V

doi:10.1046/j.1442-200x.2001.01397.x

Evaluation of DNA damage using the comet assay in children on long-term benzathine penicillin for secondary prophylaxis of rheumatic fever

Atıf İçin Kopyala

Dundaroz R., Ulucan H., Denli M., Karapinar K., Aydin H., Baltaci V.

PEDIATRICS INTERNATIONAL, cilt.43, sa.3, ss.276-280, 2001 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 43 Sayı: 3
Basım Tarihi: 2001
Doi Numarası: 10.1046/j.1442-200x.2001.01397.x
Dergi Adı: PEDIATRICS INTERNATIONAL
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.276-280
Bursa Uludağ Üniversitesi Adresli: Hayır

Özet

Backround: Benzathine penicillin is the most widely used antibiotic in the prophylaxis of children with rheumatic fever. The aim of the present study was to evaluate the DNA damage in children receiving one dose of 1.2 million units benzathine penicillin every 4 weeks over a long period to prevent recurrences of rheumatic fever.