Association of the 5HTR2C gene Ser23 variation with childhood allergic asthma

TEMEL Ş. G., Ergoren M. C., Yilmaz I., Yuruker O., Cobanogullari H., Tosun O., ...More

EUROBIOTECH JOURNAL, vol.6, no.3, pp.126-132, 2022 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 3
  • Publication Date: 2022
  • Doi Number: 10.2478/ebtj-2022-0013
  • Journal Name: EUROBIOTECH JOURNAL
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
  • Page Numbers: pp.126-132
  • Keywords: Childhood Allergic Asthma, Atopy, 5HTR2C, rs6318, RECEPTOR POLYMORPHISMS, SEROTONIN, STRESS, DEPRESSION, RESPONSES, CYS23SER, 2C
  • Bursa Uludag University Affiliated: Yes

Abstract

Objective: Allergic asthma is the most frequently observed subtype of individuals with asthma. The effects of serotonin plays in the pathophysiology of asthma has not been clearly determined. Thus, this study aimed to investigate the association between the 5HTR2C gene rs 6318 G>C polymorphism and allergic asthma in pediatric patients in Cyprus.