The Effect of Alkalinized Bupivacaine in Infraclavicular Brachial Plexus Blockade I̊nfraklaviküler Brakiyal Pleksus Blokajinda Alkalinize Bupivakainin Etkisi
Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi, cilt.31, sa.7, ss.353-357, 2003 (Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 31 Sayı: 7
- Basım Tarihi: 2003
- Dergi Adı: Turk Anesteziyoloji ve Reanimasyon Dernegi Dergisi
- Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.353-357
- Anahtar Kelimeler: Brachial plexus block, Bupivacaine, Sodium bicarbonate
- Bursa Uludağ Üniversitesi Adresli: Evet
Özet
The aim of the current study is to determine the effects of alkalinized bupivacaine 0.25% on the time of onset of sensory and motor blockade and duration of postoperative analgesia during infraclavicular brachial plexus blockade. In this double-blind study, fifty ASA physical status I ve II patients were randomly allocated into two groups. Group 1 (n=25) received 30 mL of bupivacaine 0.25% (pH=6.6), while Group 2 (n=25) received 30 mL of alkalinized bupivacaine 0.25% (pH=7.4). The onset of sensory and motor blockade was significantly shorter in Group 2 (p<0.0001). The duration of postoperative analgesia was found to be significantly longer in Group 2 (p<0.0001). As a conclusion; the alkalinization of bupivacaine 0.25% solution provides clinical advantage in infraclavicular brachial plexus blockade when compared with commercially available bupivacaine.