Development and application of a solid phase extraction method for the determination of phthalates in artificial saliva using new synthesised microspheres


OSMAN B., Ozer E., Besirli N., Gucer S.

POLYMER TESTING, vol.32, no.4, pp.810-818, 2013 (Peer-Reviewed Journal) identifier identifier

  • Publication Type: Article / Article
  • Volume: 32 Issue: 4
  • Publication Date: 2013
  • Doi Number: 10.1016/j.polymertesting.2013.03.017
  • Journal Name: POLYMER TESTING
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.810-818
  • Keywords: Phthalate, Gas chromatography mass spectrometry poly(EGDMA-MATrp), Saliva, Central composite design, CHROMATOGRAPHY-MASS-SPECTROMETRY, DIETHYL PHTHALATE, ACTIVATED CARBON, AQUEOUS-PHASE, ESTERS, MICROEXTRACTION, MIGRATION, PLASTICIZERS, ADSORPTION, PRODUCTS

Abstract

This paper describes a method for the determination of six phthalate esters (PEs) in artificial saliva using solid phase extraction (SPE) and gas chromatography-mass spectrometry (GC-MS). A new material was developed to isolate the PEs from artificial saliva. Poly(ethylene glycol dimethacrylate-N-methacryloyl-L-tryptophan methyl ester) (poly(EGDMA-MATrp)) microspheres (average diameter = 106-300 mu m) were synthesised and characterised.